2020.
Ahel, J., Lehner, A., Vogel, A., Schleiffer, A., Meinhart, A., Haselbach, D., Clausen, T.Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism
eLife, 2020;9:e56185
Sonn-Segev, A., Belacic, K., Bodrug, T., Young, G., VanderLinden, R. T., Schulman, B.A., Schimpf, J., Friedrich, T., Vinh Dip, P., Schwartz, T.U., Bauer, B., Peters, J.M., Struwe, W.B., Benesch, J.L.P., Brown, N.G., Haselbach, D., Kukura, P.
Quantifying the heterogeneity of macromolecular machines by mass photometry
Nat Commun. 11: 1772
2019.
Prajapati, S., Haselbach, D., Wittig, S., Patel, MS., Chari, A., Schmidt, C., Stark, H., Tittmann, K.Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters
Structure. 27(7):1124-1136.e4
Watson, ER., Grace, CRR., Zhang, W., Miller, DJ., Davidson, IF., Prabu, JR., Yu, S., Bolhuis, DL., Kulko, ET., Vollrath, R., Haselbach, D., Stark, H., Peters, JM., Brown, NG., Sidhu, SS., Schulman, BA.
Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site
Proc Natl Acad Sci U S A.
2018.
Haselbach, D., Komarov, I., Agafonov, DE., Hartmuth, K., Graf, B., Dybkov, O., Urlaub, H., Kastner, B., Lührmann, R., Stark, H.Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex
Cell. 172(3):454-464.e11
2017.
Bertram, K., Agafonov, DE., Dybkov, O., Haselbach, D., Leelaram, MN., Will, CL., Urlaub, H., Kastner, B., Lührmann, R., Stark, H.Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation
Cell. 170(4):701-713.e11
Haselbach, D., Schrader, J., Lambrecht, F., Henneberg, F., Chari, A., Stark, H.
Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs
Nat Commun. 8:15578
2016.
Brown, NG., VanderLinden, R., Watson, ER., Weissmann, F., Ordureau, A., Wu, KP., Zhang, W., Yu, S., Mercredi, PY., Harrison, JS., Davidson, IF., Qiao, R., Lu, Y., Dube, P., Brunner, MR., Grace, CRR., Miller, DJ., Haselbach, D., Jarvis, MA., Yamaguchi, M., Yanishevski, D., Petzold, G., Sidhu, SS., Kuhlman, B., Kirschner, MW., Harper, JW., Peters, JM., Stark, H., Schulman, BA.Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C
Cell. 165(6):1440-1453
Qiao, R., Weissmann, F., Yamaguchi, M., Brown, NG., VanderLinden, R., Imre, R., Jarvis, MA., Brunner, MR., Davidson, IF., Litos, G., Haselbach, D., Mechtler, K., Stark, H., Schulman, BA., Peters, JM.
Mechanism of APC/CCDC20 activation by mitotic phosphorylation
Proc Natl Acad Sci U S A. 113(19):E2570-8
Yamaguchi, M., VanderLinden, R., Weissmann, F., Qiao, R., Dube, P., Brown, NG., Haselbach, D., Zhang, W., Sidhu, SS., Peters, JM., Stark, H., Schulman, BA.
Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation
Mol Cell. 63(4):593-607
2015.
Chari, A., Haselbach, D., Kirves, JM., Ohmer, J., Paknia, E., Fischer, N., Ganichkin, O., Möller, V., Frye, JJ., Petzold, G., Jarvis, M., Tietzel, M., Grimm, C., Peters, JM., Schulman, BA., Tittmann, K., Markl, J., Fischer, U., Stark, H.ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space
Nat Methods. 12(9):859-65
2013.
Dölker, N., Blanchet, CE., Voß, B., Haselbach, D., Kappel, C., Monecke, T., Svergun, DI., Stark, H., Ficner, R., Zachariae, U., Grubmüller, H., Dickmanns, A.Structural determinants and mechanism of mammalian CRM1 allostery
Structure. 21(8):1350-60
Monecke, T., Haselbach, D., Voß, B., Russek, A., Neumann, P., Thomson, E., Hurt, E., Zachariae, U., Stark, H., Grubmüller, H., Dickmanns, A., Ficner, R.
Structural basis for cooperativity of CRM1 export complex formation
Proc Natl Acad Sci U S A. 110(3):960-5
2011.
Köster, DM., Haselbach, D., Lehrach, H., Seitz, H.A DNAzyme based label-free detection system for miniaturized assays
Mol Biosyst. 7(10):2882-9